COST-EFFECTIVENESS ANALYSIS OF TREATMENT TIMING CONSIDERING THE FUTURE ENTRY OF LOWER-COST GENERICS FOR HEPATITIS C

Cost-effectiveness analysis of treatment timing considering the future entry of lower-cost generics for hepatitis C

Katherine Heath1,2 1Mathematical Ecology Research Group, Department of Zoology, University of Oxford, Oxford OX1 3PS, UK; 2New College, Oxford OX1 3BN, UK Background: Cost-benefit analyses are crucial to inform treatment policies, particularly when the cost of patented drugs is very high.The cost of patented drugs is the limiting factor in hepatiti

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Exploring the hidden connections between information channel use and pro-environmental behavior among recreational anglers of the shore-based shark fishery in Florida, United States

IntroductionShore-based shark fishing in Florida is a relatively low-cost and easy-access fishery which attracts a wide variety of experienced and inexperienced anglers leading to concerns about proper handling methods of captured fish that are released either voluntarily or to comply with regulations.Proper handling methods can help reduce post-re

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Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study.

In mammalian cells, de novo glycerolipid synthesis begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferases (GPAT).GPAT2 is a mitochondrial isoform primarily expressed in testis under physiological conditions, and overexpressed in several types of cancers and cancer-derived human cell lines where its exp

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